P640
“The synthesis of compounds for commercial and medical use is a common application of organic chemistry. By altering the molecular structure of common compounds, chemists have come up with synthetic products that can be used by millions of people everyday.
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For example, due to growing concerns about diabetes and obesity in the U.S. population, artificial sweeteners were created as alternatives to sugar. Today, artificial sweeteners are used in a large number of beverages and pre-packaged foods. One such compound is Aspartame (Figure 1), a dipeptide that is approximately 200 times sweeter than sucrose.
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Other compounds have more direct medical uses. N-alkyl-pthalamides are used in a variety of drugs, including anticonvulsants and anti-inflammatory agents. The synthesis of a phthalamides can be accomplished through phthalic anhydride and RNH2 (Figure 2), where R can be various groups and thus create various products. ”
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